Sleep length and quality, sleepiness and urinary melatonin among healthy Danish nurses with shift work during work and leisure time. Int J Neurosc. An official website of the United States government. The Karolinska Sleepiness Scale (KSS) is frequently used to study sleepiness in various contexts. Die ESS scheint nach vorliegenden Daten von tageszeitlichen Vigilanzschwankungen unbeeinflusst die Tagesmdigkeit retrospektiv ber einen lngeren Zeitraum zu erfassen. Therefore, we also applied Cohens unweighted Kappa [11] across all values 19 between versions A and B. One weakness is the modest number of participants, which may have affected the analysis of the distribution of ratings. Epub 2022 Jan 31. The Karolinska Sleepiness Scale (KSS) is frequently used to study sleepiness in various contexts. uneven) step (1, 3, 5, 7, and 9). Still, the study gives a reasonable impression of the similarity of the two versions, also when considering the pattern across time [9]. The results show a clear circadian pattern, with high values during the morning (4.5 at 07:00 hours) and evening (6.0 at 22:00 hours), and with low values (3-4) during the 10:00-16:00 hours span. 1 shows that there was more frequent use of steps 7 and 8 in version B and a less frequent use of step 9 and 3. Original study: kerstedt, T. and Gillberg, M. Subjective and objective sleepiness in the active individual. [8] added labels to the remaining four (even) steps. The .gov means its official. Would you like email updates of new search results. Using the Karolinska Sleep Questionnaire to identify - PubMed MeSH CAS PubMed Central An erratum to this article is available at https://doi.org/10.1007/s41105-017-0111-0. PubMed For this purpose the McNemar test [10] was applied to compare the distribution of frequency of use of even and odd values for the two versions. The two versions were here compared in a 24hr wakefulness study of 12 adults. 8600 Rockville Pike Hilditch CJ, Wong LR, Bathurst NG, Feick NH, Pradhan S, Santamaria A, Shattuck NL, Flynn-Evans EE. Validation of the Karolinska sleepiness scale against performance and EEG variables. Epub 2017 Jul 31. How to Design a Relevant Corpus for Sleepiness Detection Through Voice? In the study mentioned, alpha and . International Journal of Neuroscience, 52, 2937. Accessibility PubMed Ergonomics, 36, 100717. NeuroRehabilitation 35(2):245251. New Data Presented at World Sleep Congress Demonstrate Early Signs of Efficacy for TAK-925, a Selective Orexin Type-2 Receptor (OX2R) Agonist, in Patients with Narcolepsy Type 1. 2018;67:5565. Gewidmet Prof. Dr. Wolfgang Pirsig, als Pionier der deutschen HNO-rztlichen Schlafmedizin. Construction and validation of the EEG analogues of the Karolinska References . Int J Neurosci 52(12):2937, Article Diagnostic accuracy of the apnea/snoring and sleepiness indices for OSAS was poor but could be improved by combining clinical and KSQ items. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). st8=diG;t2_(Nz$Yb9'#dEi_ Countless innovations. Sleepiness, sleep duration, and human social activity: An - PNAS These results suggest that use of a selective OX2R agonist may be an effective approach to treating excessive daytime sleepiness in NT1.In individuals with NT1, TAK-925 showed increased wakefulness compared to placebo. H(%-cB,4`Kpc^CO]c?HhZE4Bc*}A!>"?LG4/dhYyO\4| :TIxN>9 National Library of Medicine CAS Sleep and recovery in physicians on night call: a longitudinal field study. New Data Presented at World Sleep Congress Demonstrate Early - Takeda Karolinska Sleepiness Scale (KSS). The KSS and SSS scores revealed acircadian rhythm-dependent curve with increased sleepiness at noon and in the evening. The KSS is a measure of situational sleepiness. MeSH Chronobiol Int 21(45):673690, Kribbs NB, Pack AI, Kline LR etal (1993) Effects of one night without nasal CPAP treatment on sleep and sleepiness in patients with obstructive sleep apnea. Accessibility Grigg-Damberger M, Gozal D, Marcus CL, Quan SF, Rosen CL, Chervin RD, Wise M, Picchietti DL, Sheldon SH, Iber C. J Clin Sleep Med. Takeda undertakes no obligation to update any of the forward-looking statements contained in this press release or any other forward-looking statements it may make, except as required by law or stock exchange rule. Validation of the Colombian version of the Karolinska sleepiness scale. Subjective and objective sleepiness in the active individual. This study was conducted as a single-center, randomized, double-blind, placebo- and active-controlled, crossover design in 20 sleep-deprived healthy male adults. Methods. Data source: Provided by the Springer Nature SharedIt content-sharing initiative, Over 10 million scientific documents at your fingertips, Not logged in Bethesda, MD 20894, Web Policies Google Scholar. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Sleep 28(4):499521, Lee SJ, Kang HW, Lee LH (2011) The relationship between the Epworth Sleepiness Scale and polysomnographic parameters in obstructive sleep apnea patients. Martin VP, Rouas JL, Micoulaud-Franchi JA, Philip P, Krajewski J. However, it exists in two versions, one with labels on every other step (version A), and one with labels on every step (version B) on the 9-point scale. Ohayon MM. KSS ratings were obtained every hour, alternating version A and B. Epub 2007 Apr 26. Driver sleepinessevaluation of reaction time measurement as a secondary task. Sleepiness affects a large part of the population and is usually increased in relation to shift work or disturbed sleep [1]. https://doi.org/10.1007/978-1-4419-9893-4_47, DOI: https://doi.org/10.1007/978-1-4419-9893-4_47. See this image and copyright information in PMC. doi: 10.1016/j.jpsychires.2011.06.008. kerstedt T, Gillberg M. Subjective and objective sleepiness in the active individual. The site is secure. The Karolinska Sleepiness Scale (KSS) and the Stanford Sleepiness Scale (SSS) served as references for the detection of present sleepiness at three different measurement times (morning, noon, evening), prior to and following adiagnostic polysomnography night as well as after acontinuous positive airway pressure (CPAP) titration night (9measurements in total). Cohen J. Objetivo: Sleep 15(4):376381, Johns MW (1993) Daytime sleepiness, snoring, and obstructive sleep apnea. Original study: kerstedt, T. and Gillberg, M. Subjective and objective sleepiness in the active individual. Population for Testing This site needs JavaScript to work properly. Provided by the Springer Nature SharedIt content-sharing initiative, Over 10 million scientific documents at your fingertips, Not logged in PDF Fatigue Reduction: How Alert Are You? - Network Rail https://doi.org/10.1007/s00106-016-0270-3, DOI: https://doi.org/10.1007/s00106-016-0270-3. Introduction: Clin Otolaryngol Allied Sci 24(3):239241, Philip P (2005) Sleepiness of occupational drivers. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions.For more information, visit https://www.takeda.comForward-Looking StatementsThis press release and any materials distributed in connection with this press release may contain forward-looking statements, beliefs or opinions regarding Takedas future business,future position and results of operations, including estimates, forecasts, targets and plans for Takeda. 0 Where can I find the Karolinska Sleep Questionnaire? The Karolinska Sleepiness Scale (KSS) is frequently used to study sleepiness in various contexts. Bookshelf Assessing sleepiness and cataplexy in children and adolescents with narcolepsy: a review of current patient-reported measures. Sensitivity was 0.76 (95% confidence interval 0.630.86) and specificity 0.88 (0.740.96). Significance: PubMed The KSS spans 9 levels (1=extremely alert, 2=very alert, 3=alert, 4=rather alert, 5=neither alert nor sleepy, 6=some signs of sleepiness, 7=sleepy, but no effort to keep awake, 8=sleepy, some effort to keep awake, 9=very sleepy, great effort keeping awake, fighting sleep). The site is secure. A mdia da qualidade metodolgica dos estudos foi de 16,11,9 pontos. - 167.172.64.181. doi: 10.1371/journal.pone.0045987. The eligibility criteria were studies published in English and Portuguese, original articles that used questionnaires to assess EDS and whose sample consisted of Brazilian children and/or adolescents. On this scale subjects indicate which level best re ects the psycho-physical sate experienced in the last 10 min. Would you like email updates of new search results? KSP measures the personality with a 135 item questionnaire with answers on a four-point Likert scale. Narcolepsy Network. HHS Vulnerability Disclosure, Help Profiles of Subjective Daytime Sleepiness through Cluster Analysis, Psychometric properties and accuracy of the European Portuguese version of the Pittsburgh Sleep Quality Index in clinical and non-clinical samples, Nonrestorative sleep scale: reliable and valid for the Chinese population, Validation of the sleep hygiene index for the elderly, Associations Between Intraindividual Variability in Sleep and Daily Positive Affect, https://doi.org/10.1007/s41105-017-0111-0, https://creativecommons.org/licenses/by/4.0/. Google Scholar, Kecklund G, Akerstedt T (1993) Sleepiness in long distance truck driving: an ambulatory EEG study of night driving. The main question concerned whether the two versions would differ in the distribution of choices of even and odd values. Using the Karolinska Sleep Questionnaire to identify obstructive sleep apnea syndrome in a sleep clinic population Diagnostic accuracy of the apnea/snoring and sleepiness indices for OSAS was poor but could be improved by combining clinical and KSQ items. Am J Respir Crit Care Med 162(4 Pt 1):15121517. . Revisar sistematicamente a literatura sobre os instrumentos utilizados para avaliar a sonolncia diurna excessiva (SDE) em crianas e adolescentes brasileiros. The testing of the correspondence between the two scales did not show any significant difference with respect to the labeled and unlabeled parts of the scales. official website and that any information you provide is encrypted government site. %PDF-1.5 % Furthermore, the average variance explained was r Kaida K, Akerstedt T, Kecklund G, Nilsson JP, Axelsson J. The instruction asks the user to circle the number that represents the perceived level of sleepiness during the immediately preceding 5min. Bethesda, MD 20894, Web Policies 2021 Sep 22;3:686068. doi: 10.3389/fdgth.2021.686068. This process is experimental and the keywords may be updated as the learning algorithm improves. In addition, the two versions were highly correlated across time. The weighted Kappa values was K=0.73, with a 95% confidence interval of 0.650.83. Stanford Sleepiness Scale and Karolinska Sleepiness Scale. JSleep Res 7(4):248253, Osman EZ, Osborne J, Hill PD, Lee BW (1999) The Epworth Sleepiness Scale: can it be used for sleep apnoea screening among snorers? NCI CPTC Antibody Characterization Program, Crowley SJ, Wolfson AR, Tarokh L, Carskadon MA. Objective: 1994 Apr;17 (3):236-41 ( Pubmed abstract) doi:10.1007/s00405-011-1808-3, Lu W, Cantor J, Aurora RN etal (2014) Variability of respiration and sleep during polysomnography in individuals with TBI. Validation of the Karolinska sleepiness scale against - PubMed J Sleep Res. I think I'm sleepy, therefore I am - Awareness of sleepiness while sharing sensitive information, make sure youre on a federal Correspondence to The SSS is free to the general public and can be found in many forms online. Miley A, Kecklund G, kerstedt T. Comparing two versions of the Karolinska Sleepiness Scale (KSS). Part of Springer Nature. The answers are grouped into 15 scales: This page is not available in other languages. and transmitted securely. There was also a possibility that the distribution across all the individual values 19 would be affected by the labeling. The .gov means its official. The original scale (A, see methods) had labels on every second (i.e. Unauthorized use of these marks is strictly prohibited. Thus, the value of version A at 08:00 was paired with the value at 09:00 of version B, etc. This approach was chosen since rating sleepiness on both scale at the same time would very likely have led to a strong carryover from one scale to the other. PMC Zirkadianer Rhythmus | SpringerLink JBiol Rhythms 17(6):548555, Koscec A, Radosevic-Vidacek B (2004) Circadian components in energy and tension and their relation to physiological activation and performance. The primary endpoint was total sleep time (TST) and the key secondary endpoint was mean MSLT latency. Sleep 27(3):541548, Newell J, Mairesse O, Verbanck P, Neu D (2012) Is a one-night stay in the lab really enough to conclude? English, Because waiting times for specialized OSAS care remain long, an accurate screening tool to exclude low-risk patients from diagnostic testing would be valuable. The values from version A and version B were also correlated for each individual across time points. FOIA In Scandinavia, portable monitoring has virtually replaced standard polysomnography for diagnosis of obstructive sleep apnea syndrome (OSAS). Methods: Akerstedt T, Gillberg M. (1990). J Psychiatry Res. 2023 Springer Nature Switzerland AG. Malheiros LEA, da Costa BGG, Lopes MVV, Chaput JP, Silva KS. Validation of the Karolinska sleepiness scale against performance and When all scale values were compared the exact comparison showed a significant difference whereas the weighted one did not. Federal government websites often end in .gov or .mil. These findings suggest that the labeling of step 8 may have made it easier not to rate 9 when very sleepy. A.Bedorf, C.Rohrmeier, T.Khnel, B.Herzog, T.Bremert, S.Plontke und S.Pll geben an, dass kein Interessenkonflikt besteht. Sleep, 17, 236241. Retrospectively, we combined six KSQ items (snoring, breathing cessations, disturbed sleep, etc.) doi:10.1164/ajrccm.162.4.9911073, Guimaraes C, Martins MV, Vaz Rodrigues L, Teixeira F, Moutinho Dos Santos J (2012) Epworth Sleepiness Scale in obstructive sleep apnea syndrome an underestimated subjective scale. Objective Assessment of Sleep Patterns among Night-Shift Workers: A Scoping Review. E-R models were developed to describe exposure-efficacy (HAMD-17, SDS, and Clinical Global Impression-Improvement [CGI-I] scale) and exposure-safety relationships (Karolinska Sleepiness Scale [KSS], Massachusetts General Hospital Sexual Functioning Inventory [MGH-SFI], and adverse events [AEs] of headache, sedation, and somnolence) relationships. Karolinska Sleepiness Scale results generally reflected the results obtained on the MWT. The purpose of this brief report is to compare the distribution of ratings across the two versions and to analyze the covariation between the two scales over 24h of wakefulness. This tests the absolute correspondence between the ratings for each level of the two versions. 2001;24(6):6958. The site is secure. Using the Karolinska Sleep Questionnaire to identify obstructive sleep Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden, Stress Research Institute, Stockholm University, Stockholm, Sweden, You can also search for this author in Two centuries. Can physiological sleepiness underlie consciously perceived sleepiness assessed with the Epworth sleepiness scale? 1, 3, 5, 7, and 9) and 56 ratings for non-labeled (even) values (i.e. PubMedGoogle Scholar. . M. Herzog. The two scales were used with 1h intervals and it seems unlikely that the context of continuous wakefulness should have had differing effects on the two versions. CrossRef Von allen Patienten liegt eine Einverstndniserklrung vor. Chronobiol Int. -, Galland BC, Short MA, Terrill P, Rigney G, Haszard JJ, Coussens S, et al. They are probably less useful when administered while the patient is at the clinic; a measure would be more useful if it reflected sleepiness while driving or probed a more general 'trait', like degree of sleepiness. [3] Because it can be used to evaluate specific moments, the scale can be used repeatedly at different time intervals in a research study or for treatment intervention.[3]. To compare the two versions of the KSS, the administration of the versions alternated every hour, starting with version A (for all participants). Were encouraged by the results of these early studies and are exploring further clinical investigation of selective OX2R agonists in NT1 and other disorders characterized by excessive daytime sleepiness, such as narcolepsy type 2 and idiopathic hypersomnia, and also as a possible treatment for residual excessive daytime sleepiness in obstructive sleep apnea.Takeda also presented preclinical data on TAK-994, an oral selective OX2R agonist currently in Phase 1 clinical studies, in two posters at the World Sleep Congress. HHS Vulnerability Disclosure, Help The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Inspection of Fig. -, Lo JC, Groeger JA, Santhi N, Arbon EL, Lazar AS, Hasan S, et al. KSS ratings were obtained every hour, alternating version A and B. JPsychosom Res 49(5):367372, Contardi S, Pizza F, Sancisi E, Mondini S, Cirignotta F (2004) Reliability of a driving simulation task for evaluation of sleepiness. Conclusions: Epub 2013 Mar 6. We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. Sleep. Correspondence to This scale measures the subjective level of sleepiness at a particular. The Kappa value was in the range of good correspondence. Meyer C, Ferrari Junior GJ, Andrade RD, Barbosa DG, da Silva RC, Pelegrini A, Gomes Felden P. A systematic review of the literature was performed in the databases MEDLINE PubMed, Scopus, Web of Science, LILACS, Scielo and SPORTDiscus, with no time limit for searches. doi:10.1016/j.jpsychores.2004.05.004, Furuta H, Kaneda R, Kosaka K, Arai H, Sano J, Koshino Y (1999) Epworth Sleepiness Scale and sleep studies in patients with obstructive sleep apnea syndrome. Available at. 2012;46(4):422427. sharing sensitive information, make sure youre on a federal Epub 2009 Apr 26. 2001 Jul;41(3):251-63. doi: 10.1016/s0167-8760(01)00138-6. sharing sensitive information, make sure youre on a federal Meanse KSS values from two-way ANOVA for each point in time for versions A and B during 24h of continuous wakefulness. Results: Please enable it to take advantage of the complete set of features! J Neural Transm 121(Suppl 1):3340. PMC Sleep. 2016;14 (3):257-260 ( Full Text article) Gillberg M, Kecklund G, Akerstedt T. Relations between performance and subjective ratings of sleepiness during a night awake. HNO 65, 154162 (2017). Google Scholar, Chica-Urzola HL, Escobar-Cordoba F, Eslava-Schmalbach J (2007) Validating the Epworth Sleepiness Scale (Validacion de la Escala de Somnolencia de Epworth). This is somewhat unexpected, although the participants using version A are always encouraged to use also the unlabeled steps when carrying out their ratings. All rights reserved. Int J Psychophysiol. https://doi.org/10.1007/s00106-016-0270-3. (2006). hb```a`` (2*wIbe400v B1}^=r;umfPX"ilJt'rVF $g,0 Al This study was supported by the Swedish Research Council for Health, Working Life and Welfare. Disclaimer. 8600 Rockville Pike Percept Mot Skills. On this scale subjects indicate which level best reflects the psycho-physical sate experienced in the last 10 min. The subjects were asked if certain symptoms of sleepiness had . PubMed Careers. Int J Psychophysiol. The meeting was held in Vancouver, Canada from September 20-25, 2019. doi:10.1016/j.brainresbull.2003.12.016, Czeisler CA, Duffy JF, Shanahan TL et al (1999) Stability, precision, and near-24-hour period of the human circadian pacemaker. The aim of this study is to investigate the influence of circadian rhythm-dependent alertness on ESS performance. CrossRef Before 2021 Dec 15;18(24):13236. doi: 10.3390/ijerph182413236. Sugere-se que pesquisas futuras relacionadas SDE em crianas e adolescentes faam a validao no Brasil de outros instrumentos e apresentem os valores de consistncia interna. Comparing two versions of the Karolinska Sleepiness Scale (KSS) Felden P, Carniel JD, Andrade RD, Pelegrini A, Anacleto TS, Louzada FM. RACGP - Evaluation of the sleepy patient - Australian Family Physician Relations between performance and subjective ratings of sleepiness during a night awake. Herzog, M., Bedorf, A., Rohrmeier, C. et al. Psychometrika. Clin Neurophysiol 117(7):15741581. 2007;45(4):5206. An erratum to this article has been published. Instrument score ranged between 0 and 21; a higher score indicated more severe symptoms. Participants were 16 healthy females aged 33-43 (38.1+/-2.68) years. The sleep deprivation setting has the advantage of making possible comparisons at many different levels of sleepiness. National Library of Medicine The main aim of the present study was to investigate the validity and reliability of the KSS with electroencephalographic, behavioral and other subjective indicators of sleepiness. PubMed Central PDF Quantitative measurements of sleepiness - Helsinki Cohen J. official website and that any information you provide is encrypted What is equally exciting is that we also saw wake-promoting effects in healthy individuals, who are presumed to have normal orexin levels. CAS ACM Arq Catarin Med. Gillberg M, Kecklund G, Akerstedt T. (1994). doi:10.1016/j.clinph.2006.03.011, Kapur VK, Baldwin CM, Resnick HE, Gottlieb DJ, Nieto FJ (2005) Sleepiness in patients with moderate to severe sleep-disordered breathing. Excessive daytime sleepiness prevalence and associated factors in teen University student from the Southern of Santa Catarina. The Karolinska Sleepiness Scale (KSS) and the Stanford Sleepiness Scale (SSS) served as references for the detection of present sleepiness at three different measurement times (morning, noon, evening), prior to and following a diagnostic polysomnography night as well as after a continuous positive airway pressure (CPAP) titration night (9 Kaida K, Akerstedt T, Takahashi M, Vestergren P, Gillberg M, Lowden A, et al. 6=some signs of sleepiness . 2022 Jan-Mar;15(Spec 1):97-104. doi: 10.5935/1984-0063.20220006. 36 0 obj <>/Filter/FlateDecode/ID[<32B9D8560D640D2D1187A9774A049956><7C2732CB22C4D4468293E0843A108806>]/Index[17 44]/Info 16 0 R/Length 94/Prev 76775/Root 18 0 R/Size 61/Type/XRef/W[1 2 1]>>stream Unauthorized use of these marks is strictly prohibited. The number of ratings for each level of the two scales is presented in Fig. An official website of the United States government. The two versions have not been compared with respect to distribution of ratings, however. J Psychiatry Res. The answers are grouped into 15 scales: Psychic anxiety Somatic anxiety Muscular tension Psychasthenia Performance prediction by sleepiness-related subjective symptoms during 26h sleep deprivation. 60 0 obj <>stream To this was also applied Bowkers test of symmetry [13] for significance testing. Rev Salud Publica (Bogota) 9(4):558567, Article This test is based on the power density of the EEG during 'eyes-open' or 'eyes-closed'. Epub 2019 Jul 12. Sixteen articles were selected, in which nine different instruments were applied to 8.240 children and adolescents from the South, Southeast, Midwest and Northeast regions of Brazil. Google Scholar.

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