This fact, coupled with the rising trend of such diseases, means that priority should be given towards preventive measures. To do so, increase one pot size every year. Bioref. 3RD BIOMEDICAL ENGINEERINGS RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES : Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2018, Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia. Further research suggestions on the investigation of AI are using longer time of treatment and other test subjects.". Search for other works by this author on: Faculty of Medicine, Universitas Indonesia, Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. The plant Acalypha indica is commonly known as Indian Acalypha and it belongs to the family Euphorbiaceae. When new growth emerges, you can remove the bag and move the plant to its more permanent location. During the winter months, cut back on feeding or stop entirely. Further, this formulation was supplemented with Acalypha indica extract to prepare the green soap, and its antifungal activity was determined using the agar dilution method. (1999) Preliminary screening of ethnomedicinal plants from India, J Ethnopharmacol. (AI) is known to have flavonoids and polyphenols which may decrease LDL and increase HDL level. Seven cyanopyridone derivatives (Acalyphin, Epiacalyphin, Noracalyphin, Epinoracalyphin, Acalyphin amide, Epiacalyphin amide cycloside, ar-Acalyphidone and one corresponding seco compound (seco-Acalyphin) have been isolated from methanolic extract of Acalypha indica leaves [9]. session so others can sign in. 2015 Jul 1;169:441-58. doi: 10.1016/j.jep.2015.04.042. These showy broadleaf evergreens are native to the south pacific islands and Southeast Asia where they grow in warm, tropical, and humid habitats. If you notice a sign of infestation, isolate the troubled plant immediately and treat it with a mild insecticide or horticultural oil like neem oil. Indonesia is home to diverse sorts of vegetations as an agricultural power, such as Acalypha indica L. (AI). This site needs JavaScript to work properly. illeg. Different pharmacological experiments in both in vitro and in vivo have been carried out and also identified the medicinally important phyto-constitutents. WebThe pharmacological studies conducted on Acalypha indica indicate the immense potential of this plant in the treatment of conditions such as wounds, malaria, coughs, official website and that any information you provide is encrypted The chenille plant has all the same uses as the copperleaf but is also especially attractive in hanging containers. Optimization results revealed that the formulation containing 44.57% A, 23.62% B, 17.44% C, 5.37% D, and 9.0% E would yield 41 Y1, 62 Y2, and 159 Y3. Objective: This study aimed to assess the Deadheading the flowers of the chenille plant before they completely die off will stimulate vigorous new flower growth. WebAcalypha indica is also effective to control water-borne pathogenic bacterial at smaller concentration (10 ug/mL) (Krishnaraj et al., 2010). Results: [20] Ruchi GM, O.F. 4 0 obj The hexane, chloroform, ethyl acetate and methanol extracts from the leaves of Acalypha indica were evaluated for antibacterial activities against gram positive (Staphylococcus aureus, Staphylococcus epidermidis, Bacillus cereus, Streptococcus faecalis) and gram negative (Klebsiella pneumoniae, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa) bacteria. After four weeks of treatment, rats were terminated and laboratory test was performed to see plasma insulin level using enzyme-linked immunosorbent assay. Contact Dermatitis 34(3):165171, Article Although acalyphas are considered low-maintenance plants, they are fast-growing, and youll probably want to prune these plants to achieve a denser growth form. Webphytochemical screening of acalypha indica l. leaf extracts 1 R.Tamil Selvan, 2 A.K.Sultan Mohideen*, 3 M.Asrar Sheriff and 4 N.Md.Azmathullah PG & Research Dept. The highest oviposition effective attractancy observed was 90.09%, 94.20%, 85.43% and 95.75% for benzene, chloroform, ethyl acetate and methanol extracts respectively [19]. Other pests like scale and aphids could also affect this plant, especially if grown in partial shade. The ayurvedic formulations of Acalypha indica are used in the form of infusion, powder, succus (expressed juice), tincture, liquid extract, cataplasm and decoction. Click the button below to search for your institution on Shibboleth and OpenAthens. The genus Achyranthes: A review on traditional uses, phytochemistry, and pharmacological activities. Treat these cuttings with root hormone powder for the best results. Diabetes Res Clin Pract. As well as being exploited for medicinal use, the roots of this plant are known to elicit a drug-like However, they also tend toward legginess, which is the primary reason for regular repotting and pruning. % The male flowers are minute and crowded distally with 8 stamens. represented, 50,000 It is used in case of acrid, diuretic, cathartic, expectorant, ernetic, anodyne, hypnotic, gastrointestinal irritation, laxative, bronchitis. The fresh juice of Acalypha indica leaves was investigated for anti-inflammatory activity in four groups of overnight fasted albino rats. Rats were divided into four groups, the negative control (placebo), positive control using 6 IU vitamin E, treatment group using 250 mg/kg of body weight (mg/kg BW) AI extract, and control using young rats. <> full text articles and transmitted securely. (2004) Reviews on Indian medicinal plants. and transmitted securely. Cupamenis indica (L.) Raf. This review updates the information of Acalypha indica studies from several aspects such as phytochemical content, pharmacological activities, and ethnomedicinal The leaves are 2.5-7.5cm long and 2-2.5cm broad. Part of Springer Nature. 70:270-277. (2009) Cyanogenic and non-cyanogenic pyridine glucoside from Acalypha indica (Euphorbiaceae). This smaller species grows to just 18 inches (45 cm) tall and produces beautiful red flower spikes up to 3 inches (7.5 cm) long. The Acalypha indica plant is reported to have some of the therapeutic properties which are used in Siddha and Ayurveda as medicines. However, the usage of synthetic antioxidants chronically may Unauthorized use of these marks is strictly prohibited. Provided by the Springer Nature SharedIt content-sharing initiative, Over 10 million scientific documents at your fingertips, Not logged in It has thin egg shaped leaves with smooth surface. Hydroethanolic extract of the inner stem bark of Cedrela odorata has low toxicity and reduces hyperglycemia induced by an overload of sucrose and glucose. The site is secure. National Library of Medicine Diuretic activity of methanolic extract of Acalypha indica was evaluated in albino mice. (2004) Acaricidal property of kuppaimeni (Acalypha indica) against natural Psoroptes cuniculi infestation in broiler rabbits, Indian J Anim Sci. Prev Nutr Food Sci. Bookshelf f]j`5J\0+B!!]>a- u+}~@oQI9h=DJ@n[ ed5 xJ$#(*Xv5'mq%)o2%[?aNZtU:F[B%ax#vZ3bDl6o3;`@?G@5" b8xNU "-)7y"dSM4wF]Xe(^l>;NN^Be!QAY(`*|o1x:P%& Australas Med J. 9k;D(!P 4uc^A2|!c =fn9DA;Th50!J.k}ZZ8%,W6L"Fau{16@f?Z6-[rAVx>0b[E.~)!g~z@- (tigers milk mushrooms) in Malaysia - A review. GOEL Publishing House, Meerut, Ahmed I (1984) Palm Oil Research Institute of Malaysia (PORIM). Acalypha indica Linn (AI), is widely used as an herbal medicine for various diseases. Their versatility and their ability to grow fast and survive as annuals in cooler climates make them a great choice for your garden. Care should be taken not over-plant this species though because it really does have a bold look, wherever it is planted. We want to hear from you. ;[gAl"tgzviKdm$e9. 3 0 obj Royal Botanic Gardens, Kew, UK. Learn more about Institutional subscriptions, Vijay M (1940) The Drug and Cosmetics Act, 18th edn. The leaves of both species have serrated margins. Abstract. Telungu Kuppichettu, Harita-manjiri, Kuppinta or Muripindi. The % inhibition of denaturation is produced by Acalypha indica linn extract at the dose 200mg/kg, 400 mg/kg and 600 mg/kg were 44.5%, 62.2% and 81.1% respectively when compared to control. He is a professional writer whose articles on plants and horticulture have appeared in national and regional newspapers and magazines. If you can't login to CAB Direct, it's likely that your library doesn't have a subscription. The ethyl acetate, hexane and methanol extracts from the leaves, stem and roots of Acalypha indica were tested for their antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Klebsiella pneumoniae. Careers. 79:249-251. Keywords: This output contributes to the following UN Sustainable Development Goals (SDGs). Epub 2014 Oct 30. (2004) Neutralization potential of Viper russelli russelli (Russell's viper) venom by ethanol leaf extract of Acalypha indica; J Ethnopharmacol. Different leaves extracts Acalypha indica (benzene, chloroform, ethyl acetate and methanol) were tested for larvicidal, ovicidal activity and oviposition attractancy against the malarial vector Anopheles stephensi. government site. :.K>]0,rvI 6O.}cN_^_I_ rk\4]uE*"BA/%fEFk6. Thank you for your support! indica + A. asperatest) dispersed with 0.5 g of 0.05% Teepolemulsifying agent in 1 l (nal volume) of water. Further research in phytochemicals development from Acalypha indica will help to analayse therapeutic efficacy of products. It is also widespread across Asia, backyards of houses and waste places throughout the plains of India [1]. Data collected were analyzed using Saphiro-Wilk test and one-way ANOVA. It has been reported to be useful in treating pneumoniae, asthma, rheumatism and several other ailments4. [23] Das AK, F. Ahmed, N.N. This is to ensure that we give you the best experience possible. [18] Suresh Reddy J, P. Rajeswara Rao, S.R. You may have access to different export options including Google Drive and Microsoft OneDrive and citation management tools like RefWorks and EasyBib. The results indicated that the ethanol plant extract showed best inhibition amongst the other extracts being used [27]. However, the diverse pharmacological activities of Acalypha indica extracts and isolated phytochemical have been investigated in laboratory animals and the results obtained may not necessarily be portable to the situation in humans. The plant's roots and soil should never be allowed to dry out, so this could mean watering it at least once a weekif not moredepending on the environment in your home. WebDiameter of zone of inhibition exhibited by Acalypha indica ethanolic extract against tested organisms ranged between 9-15 (in mm). A. hispida is called the chenille plant, monkeys tail, red-hot cats tail, foxs tail, or the Philippines medusa. title = "Antiaging effects of Acalypha indica L. extract administration on tumor necrosis factor-a (TNF-a) protein level in major organs of aged Sprague-Dawley rats". Curr Sci. The plant is bitter to taste. official website and that any information you provide is encrypted The rats were then terminated after 28 days, and the major organs, kidneys, and hearts were examined using ELISA to look for TNF-a concentration. endobj (Q ?="4EKp;|Xop0 2UH0aH^@sX For best results, take a cutting in the spring, when new growth emerges on the plant. Find answers to questions about products, access, use, setup, and administration. Acalypha decidua Forssk. AIP Conference Proceedings 9 April 2019; 2092 (1): 030018. https://doi.org/10.1063/1.5096722. Rats were divided into four groups, the negative control (placebo), positive control using 6 IU vitamin E, treatment group using 250 mg/kg of body weight (mg/kg BW) AI extract, and control using young rats. In our previous in-vitro investigation, methanolic extract of A. indica stems (AIS) proved to be an effective a-glucosidase inhibitor, antioxidant, and well tolerated in acute and subchronic toxicity studies in albino wistar rats. Yes and no. This plant has much the same care requirements as the other copperleaf plant varieties but has the benefit of being a native species, occurring naturally in Florida and the Caribbean. Hence, this review contributes to the knowledge of Acalypha indica plant and their ethnopharmacological uses. Dive into the research topics of 'Antiaging effects of Acalypha indica L. extract administration on tumor necrosis factor-a (TNF-a) protein level in major organs of aged Sprague-Dawley rats'. <> bI8VEk0:s\#hPB]TlXk`@ Disclaimer. (1982) Acalyphin, A cyanogenic glucoside from Acalypha indica. The data was collected from online journals, magazines, and books, all of which were published in English, Malay and Indonesian. Metformin is the first-line medication prescribed for type 2 diabetes mellitus. Materials and methods: Efforts are now being made to investigate various therapeutic actions of Acalypha indica plant and their products using model systems. 64,000 The chenille plant is usually a little larger at 4 to 6 ft (1.2 to 1.8 m) tall and 6 to 8 ft (1.8 to 2.4 m) across. 2014 Apr;10(Suppl 2):S207-13. You may have access to the free features available through My Research. However, the usage of synthetic antioxidants chronically may incur side effects and expensive. Ethnomedicinal uses, pharmacological activities, and cultivation of Lignosus spp. It has been Together they form a unique fingerprint. Phytochemical Profile, Free Radical Scavenging and Anti-Inflammatory Properties of. Cyanogenic glucoside, acalyphin,(-)-(5R,6S)-5-cyano-5--D-glucopyranosyloxy-6-hydroxy-4-methoxy-1methyl-2-(5,6-dihydro)-pyridone and in addition the 6R-epimer of acalyphin, epiacalyphin and the corresponding pair of N-demethyl derivatives are isolated from methanolic extract of the flowers and leaves of Acalypha indica and these structures are confirmed by X-ray crystallography [12]. phrase ability, 13+ http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2007.pdf, NCI CPTC Antibody Characterization Program. Generally, tropical plants make for excellent indoor specimens, as they can't be grown in much of the country outdoors. +|!C [8]. Based on literature studies, Acalypha indica has the capability to serve as anthelmintic, anti-inflammation, anti-bacterial, anti-cancer, anti-diabetes, anti This aims a comprehensive of the chemical constituents, pharmacological and clinical uses. The first species is commonly known as copperleaf or Jacobs coat but is also sometimes called the copperleaf, lance copperleaf, or copper plant. Epub 2015 Jan 3. Mater Sci-Pol 35(4):791798, Kundu MK, Deb AT, Gupta SP (1977) A simple rapid method for direct determination of total fatty matter in soaps. This is a preview of subscription content, access via your institution. Indian Council Medical Research. Accessed 26 July 2020, Sharma B (2000) Industrial Chemistry (Including Chemical Engineering). When it comes to the pH level of its soil, acalypha plants prefer alkaline or acidic blends. Many pharmacological studies of Acalypha indica have been demonstrated for their antioxidant, antimicrobial, anti-inflammatory, anti-diabetic, wound healing effect, anti-venom and anti-fertility activities, supporting its traditional uses. There are several varieties of acalypha plants that make for excellent houseplants. Extracts and chemical constituents of this plant possess useful pharmacological activities. The powder of dry leaves is used as a remedy for bed sores and the infusion of the root acts as a cathartic. The most popular, A. hispida (also known as chenille plant or red hot cat's tail) is a popular trailing plant with red, bottle-brush-like flowers that hang in tails. The chenille plant has its male and female flowers on separate plants while the copperleaf has both sexes on the same plant. ; 5th International Symposium of Biomedical Engineering, ISBE 2020 ; Conference date: 28-07-2020 Through 29-07-2020". 1:5-6. iL6f0mtsN>5q"?xPX=_m [17] Annie S, K. Rajendran, B. Ramgopal, C. Dinesh Kumar. Epub 2021 Nov 3. Four successive solvent extracts such as chloroform, ethanol, petroleum ether and aqueous of the whole plant of Acalypha indica are tested for post-coital antifertility activity in female albino rats. eCollection 2020. Thirunavukkarasu, A., Nithya, R., Sivashankar, R. et al. This study was conducted on aged Sprague-Dawley rats. Desak Gede Budi Krisnamurti, Erza Pinayungan, Rani Wardani Hakim, Erni H. Purwaningsih; The effect of Acalypha indica Linn. The results indicated that the leaves and root extracts of ethyl acetate showed quite promising inhibition of the growth of all three bacterial species and the hexane extracts showed moderate activities [24]. It contains many nerved bract and 6-8mm in diameter. (1998) Acalypha. Copyright 2017 Elsevier Ireland Ltd. All rights reserved. The Rf values of the plant extract (0.371 0.0009) and a synthetic antifungal compound, Clotrimazole (0.371) were verified by subjecting to TLC and HPLC analyses. Diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Tylophora indica (Burm. 6 0 obj (2008) Antibacterial activity of Acalypha indica L. Eur Rev Med Pharmacol Sci. Traditional uses, phytochemistry and pharmacological properties of Neolamarckia cadamba: A review. This fact, coupled with the rising trend of such diseases, means that priority should be given towards preventive measures. Unauthorized use of these marks is strictly prohibited. Copperleaf plants have male and female flowers on the same plant. !Nd"U_ezDPMUr>Z+4!EHSk Nature heals, 2, SRISTI innovations, 9. 7:89-91. 12:299-02. One such measure is the administration of antioxidants to counter the increasing inflammatory markers, such as TNF-a, in the pathogenesis of chronic non-communicable diseases. Acalypha fimbriata Baill. Rats were divided into four groups, the negative control (placebo), positive control using 6 IU vitamin E, treatment group using 250 mg/kg of body weight (mg/kg BW) AI extract, and control using young rats. (1956) Glossary of Indian Medical Plants. The objective of this research is to investigate the effect of ethanol extract AI to insulin resistance. 13, 299310 (2023). True to their tropical nature, acalypha plants like to be kept in warm and humid conditions. The relationship between Indigenous and allopathic health practitioners in Africa and its implications for collaboration: a qualitative synthesis. By continuing you agree to the use of cookies. AI administration yielded a decrease of TNF-a in both the kidneys (0.95 0.76 pg/mg in the treatment group vs. 1.37 0.41 pg/mg in the negative control) and hearts (15.43 pg/mg 2.33 in the treatment group vs. 16.50 1.33 pg/mg in the negative control), of aged SD rats, albeit insignificantly. author = "Sutanto, {Reynardi Larope} and Purwaningsih, {Erni Hernawati} and Krisnamurti, {Desak Gede Budi}". Biswas, S. Dev, M.M. Phytochem. Phyto-pharmacology of Acalypha indica: A Review, Dineshkumar, B; Vigneshkumar, P; Bhuvaneshwaran, S P; Mitra, Analava. Antihyperglycemic activity and antioxidant role of Terminalia arjuna leaf in streptozotocin-induced diabetic rats. Background: A number of varieties are available, including the A. wildensiana 'Goldsefiana', which has light green leaves that are rimmed with white. A. indica crude extract was obtained, significant phytochemicals and antibacterial activity substance for the control of numerous antibiotic resistance bacteria Acalypha plants are long-standing houseplant favoritesand for good reason. AIS recovered the liver damage caused by streptozotocin. The links between ethnomedicinal practices and scientific studies have been discussed with a fair justification. Tiwari AK, Rao JM. The results indicated that active compound present in root, leaf and stem extracts were 538, 415, 171 g/g and showed more potent in controlling Candida albicans, Aspergillus niger and Escherichia coli [26]. [13] Chopra RN, S.L. To keep your acalypha healthy and happy, give it a regular supply of water, even during the winter months. Royal Botanic Gardens, Kew. While they don't necessarily like the harsh rays that full sun provides, they can tolerate it if acclimated. Acalypha indica (AI) is one of the herbal plants that can be found in many regions of Indonesia, therefore AI can be used as a strategic alternative medication xZr7+xIYI*rHd(Q[,vAfF_q&Ozu. HHS Vulnerability Disclosure, Help It is annual herb have numerous long, angular branches, covered with softhair. [6] Nadkarni KM. a-glucosidase enzyme inhibitor potential of, a-glucosidase enzyme inhibitor potential of A. indica stems on blood glucose levels challenged, a-glucosidse enzyme inhibitor potential of, a-glucosidse enzyme inhibitor potential of A. indica stems on blood glucose levels challenged, MeSH Linear regression models were proposed to predict the responses, i.e., hardness (Y1), iodine (Y2), and iodine number saponification (INS) (Y3), and validated with a high degree of statistical accuracy (Fcal > Ftab; df = 4, p < 0.0001; R2 > 0.9950). This study was conducted on aged Sprague-Dawley rats. endobj 2: 246, Devi N, Prabhakaran J, Wahab F (2012) Phyto chemical analysis and enzyme analysis of endophytic fungifrom Centella asiatica. ~](M@2Cm=+9mAZa+5h- |k RZ6b0>~qi.@sy.jW4b[CiD-kQs~ImJo5n Water, ethanol, chloroform and hexane extracts of Acalypha wilkesiana leaves were investigated for in vitro antimicrobial activities by agar-diffusion and tube-dilution techniques. In the first few years, you might want to repot your acalypha annually in the springtime. The seeds are minute, ovoid in shape and pale brown in colors. Acalypha plants are not particularly picky about their soil conditions and can thrive in mixtures ranging from sand and loam to clay. Although this plant is a weed, Acalypha indica has been acknowledged by local people as a useful source of medicine for several therapeutic treatments. Bookshelf UR - http://www.scopus.com/inward/record.url?scp=85103498448&partnerID=8YFLogxK, BT - 5th Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, T2 - 5th International Symposium of Biomedical Engineering, ISBE 2020. abstract = "Non-communicable diseases, such as cardiovascular diseases or kidney dysfunctions, tend to have expensive and unavailable treatments. MeSH fcJ!oDN} ()Qq@(>*j.#qe Il Dwdf?B6q)Bj]3bD)"75NS6C7isPtZE+9}tEVow,y\}o[^$v#F`6D(q2Rj[)|&65n"cS&2 U{=t$|CW]" mJJ>Dw:!ggA&#g@b2[14=N|wY7hC #>B},MKYD

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